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Discover the Benefits of the Best Heart Health Supplements

Supplement Institute Review Team
Written By Supplement Institute Review Team
Last updated: May 9, 2025, 06:35 PM
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best heart health supplement

While eating healthy and staying active are crucial for maintaining a healthy heart, sometimes we need a little extra support. With beneficial ingredients like antioxidants, omega-3 fatty acids, Vitamin D, and more, the right supplement can help support your cardiovascular health while reducing your risk of heart disease.

To help you give your heart the attention it deserves, we’ve researched and reviewed some of the best heart health supplements of 2025. We found that the Purely Beneficial Resveratrol supplement offers a range of benefits for the cardiovascular and immune systems, making it stand out among the other noteworthy contenders.

View all Contents
  • Buying Guide: Heart Health Supplements
    • Ingredients
    • Quality
    • Dosage
    • Side Effects
    • Formulation
    • Research
    • Certification
  • People Also Asked
  • Building a Stronger You
  • Contributors
  • Related Reviews

Our Top Picks

  • Purely Holistic Red Yeast Rice Heart Health Supplement: Best Overall (Shop Now) →
    Read more about this product ↓
  • Secret Element Heart Health Supplement: Powerful Ingredients (Shop Now) →
    Read more about this product ↓
  • OceanBlue Heart Health Supplement: Best Taste (Shop Now) →
    Read more about this product ↓
  • MegaRed Heart Health Supplement: Most Concentrated (Shop Now) →
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  • Purely Beneficial Heart Health Supplement: Worth Mentioning (Shop Now) →
    Read more about this product ↓
  • Snap Heart Health Supplement: Improves Blood Circulation (Shop Now) →
    Read more about this product ↓
  • FreshCap Heart Health Supplement: Best Powder Supplement (Shop Now) →
    Read more about this product ↓
  • Nutricost L-Carnitine Tartrate Heart Health Supplement: Most Potent Formula (Shop Now) →
    Read more about this product ↓
  • Nutricost L-Arginine Heart Health Supplement: Best for Your Skin (Shop Now) →
    Read more about this product ↓
  • Iwi Heart Health Supplement: Best Vegan Option (Shop Now) →
    Read more about this product ↓
  • Qunol Heart Health Supplement: Ideal for Stress Management (Shop Now) →
    Read more about this product ↓
  • Nature Made Heart Health Supplement: Improves Joint Health (Shop Now) →
    Read more about this product ↓
  • Doctor's Best Heart Health Supplement: Best for Cholesterol Management (Shop Now) →
    Read more about this product ↓

The Best Heart Health Supplements of 2025

Purely Holistic Red Yeast Rice Heart Health Supplement

Best Overall
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Purely Holistic’s Red Yeast Rice Heart Health Supplement is a natural approach to managing cholesterol levels. Even better, this heart health supplement supports overall cardiovascular health, too. It’s a supplement that harnesses the power of red yeast rice. Since this heart health supplement contains a traditional ingredient known for its cholesterol-lowering properties, you can trust that it acts as an effective alternative to prescription statins. 

Enhanced with CoQ10, this heart health supplement offers additional support for heart health. It ensures a comprehensive approach to cardiovascular wellness. Designed with both quality and efficacy in mind, this heart health supplement is made from carefully sourced ingredients that ensure purity and potency. Regular use can help you maintain healthy cholesterol levels, and that’s why this supplement is at the top of our list.

Product Pros
  • Helps lower cholesterol levels 
  • Acts as a natural statin alternative 
  • Enhanced formula with cardiovascular benefits
Product Cons
  • Potential muscle pain or digestive issues 

Secret Element Heart Health Supplement

Powerful Ingredients
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Support your heart health naturally with the Secret Element Heart Health Supplement, a premium Citrus Bergamot formula designed to help maintain healthy cholesterol levels and support overall cardiovascular function. Rich in bergamot polyphenols and antioxidants, this supplement helps balance triglyceride and lipid levels while offering powerful protection against free radicals. With 1000 mg of pure bergamot extract per serving, this bioavailable formula is designed for optimal absorption, making it twice as effective as standard bergamot powders. As we age, maintaining heart health becomes even more crucial—Secret Element is here to help you stay active, energized, and in control of your wellness journey with a clean, natural, and effective solution.

Product Pros
  • Contains 1000 mg of pure citrus bergamot extract per serving
  • Helps maintain healthy cholesterol, triglyceride, and lipid levels
  • Twice as bioavailable as bergamot powders for better absorption
Product Cons
  • Requires consistent daily use for best results

OceanBlue Heart Health Supplement

Best Taste
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Take charge of your wellness with OceanBlue Omega-3 2100 Heart Health Supplement—a powerful duo designed to support your heart and keep your energy levels steady. This thoughtfully crafted supplement combines the heart-nourishing benefits of triple-strength omega-3 fish oil with CoQ10, an essential nutrient that helps power your cells. As we age, CoQ10 levels naturally decline, but this supplement helps restore what your body needs to function at its best.

Even better, it has a fresh orange flavor that means no fishy aftertaste or unpleasant burps, making it an enjoyable part of your daily routine. Plus, it’s free of gluten, GMOs, heavy metals, and allergens, so you can feel confident in what you’re putting into your body. Whether you’re looking to simplify your supplement routine or give your heart a little extra love, this 2-in-1 formula has you covered.

Product Pros
  • Omega-3 and CoQ10 boost heart health and energy
  • Clean, pure formula free from GMOs
  • Supports healthy aging
Product Cons
  • Daily use is required for best results

MegaRed Heart Health Supplement

Most Concentrated
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If you’re looking for a krill oil supplement that offers a host of impressive health benefits, the MegaRed Krill Oil is the one to try. Not only is it recommended by doctors, but it’s also packed with essential omega-3 fatty acids, EPA, DHA, astaxanthin, and phospholipids that have been scientifically proven to support heart, brain, joint, and eye health.

This krill oil is sourced from the pristine, cold waters of the Antarctic, hence, you can be assured that you’re getting the purest form of krill oil available on the market. Plus, with its phospholipid form, there’s no unpleasant fishy aftertaste. And if that’s not enough, a recent study found that taking this supplement for just 30 days can significantly increase your Omega-3 index — an indicator of heart health. With numerous five-star ratings and reviews from satisfied customers, it’s clear that this heart health supplement is a top-notch choice for anyone looking to maintain a healthy lifestyle.

Product Pros
  • Reduces inflammation and helps relieve joint pain 
  • Supports a healthy metabolism 
  • Reinforces heart health and boosts blood circulation 
Product Cons
  • Large pill can be hard to swallow

Purely Beneficial Heart Health Supplement

Worth Mentioning
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If you’re looking for a heart health supplement that is nothing less than pure and natural, Purely Beneficial Resveratrol is the way to go. This premium 1450mg blend contains exactly the right amount of ingredients for maximum nutritional value and benefits—no fillers, artificial or inferior ingredients, or harmful preservatives are included. It’s also an excellent source of rich and potent antioxidants, thanks to Vitamin C, and it comes in 180 easy-to-swallow capsules.

These heart health supplements contain an effective blend of trans-resveratrol, green tea extract, acai extract, pomegranate extract, blueberry extract, and more all-natural ingredients. This combination of pure elements offers the potential to support your cardiovascular system, improve energy levels, slow down aging, and provide other amazing benefits, making it the best overall product on this list.

Product Pros
  • All-natural ingredients
  • Boosts energy levels
  • Strengthens the immune system
Product Cons
  • Unclear effectiveness on pain relief

Snap Heart Health Supplement

Improves Blood Circulation
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Ensure a healthy heart and improved circulation with Snap Supplements heart health support. This unique product offers a natural solution to maintaining a healthy cardiovascular system, delivering a potent blend of nutrients in a 90-capsule pack. The supplements work effectively to lower blood pressure, supporting heart health, and overall well-being. This is your reliable ally for a healthy lifestyle, making it a smart inclusion in your daily routine.

The best part is their effectiveness in improving blood circulation. Regular intake of this heart health supplement aids in boosting overall heart vitality, contributing to a healthier, more active lifestyle. They’re easy to swallow and integrate into any daily supplement regime. The ability of these supplements to naturally support healthy blood circulation provides an uncompromised way to care for your cardiovascular system.

Product Pros
  • Helps maintain healthy blood pressure
  • Enhances blood circulation and flow
  • Supports healthy cholesterol levels
Product Cons
  • Has a strong garlic smell

FreshCap Heart Health Supplement

Best Powder Supplement
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Elevate your vitality and physical performance with FreshCap organic cordyceps mushroom extract powder. As a natural powerhouse of energy and adaptability, this product is sourced from pristine and organic cordyceps mushrooms. This extract powder encapsulates all of the benefits of this unique fungus, making it a supremely beneficial heart health supplement. In fact, cordyceps has been treasured for centuries thanks to its potential to enhance endurance.

Now, you can experience its rejuvenating properties in a convenient, versatile form. Unlock a new level of vitality with this mushroom extract powder. This powder has you covered as a result of its adaptogenic qualities. These features can help the body adapt to stress while maintaining balance.

Product Pros
  • Enhances energy and endurance
  • Supports kidney health
  • May aid in cancer management
Product Cons
  • Some don’t like the taste

Nutricost L-Carnitine Tartrate Heart Health Supplement

Most Potent Formula
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Unlock the potential of Nutricost L-Carnitine Tartrate 1000mg tablets, a powerhouse heart health supplement. Crafted with precision, each non-GMO, gluten-free capsule undergoes rigorous third-party testing, guaranteeing superior quality. Elevate your well-being with 500mg of L-carnitine (tartrate) in every capsule, delivering an impressive 1000mg per serving.

Step into a world of wellness with 120 capsules per bottle, offering a generous 60 servings. Embrace the purity of this formula, free from harmful additives, making it the standout choice on the market. Whether you’re a dedicated athlete recovering from a muscle injury, embarking on a weight loss journey, or simply aiming to enhance heart function, this best overall product is your ideal companion.

Product Pros
  • Boosts energy levels
  • Helps reduce muscle spasms
  • Assists in weight loss
Product Cons
  • May disrupt sleep if taken at night

Nutricost L-Arginine Heart Health Supplement

Best for Your Skin
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Nutricost L-Arginine 1000 mg amino acid tablets are the world’s answer to heart health. The brand understands how important it is to keep your heart healthy, which is why these tablets are designed to do just that. Research shows that L-arginine may improve blood flow within the heart and help to lower blood pressure. With a double-strength dose of 1000 mg and 150 tablets per bottle, you will be receiving 150 servings of the best heart health supplement on the market.

When you purchase these heart health supplements, you can rest assured that it is non-GMO, soy-free, and gluten-free. Moreover, they are manufactured in a fully GMP-compliant and FDA-registered facility, ensuring that each and every bottle is held to the highest possible standard.

Product Pros
  • Enhances natural HGH production
  • Boosts sexual performance
  • Improves skin tightness
Product Cons
  • Large pills may be hard to swallow

Iwi Heart Health Supplement

Best Vegan Option
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The Iwi Life Heart Omega-3 is a dietary supplement that supports heart health with vegan Algae Omega-3 and EPA, which maintain proper lipid levels. It offers a 30-day supply of non-GMO, plant-based, and gluten-free goodness. Its triple-patented form of Algae EPA, AlmegaPL, is clinically proven to be better absorbed by the body than fish or krill oil. Each serving also contains Omega-3, 6, 7, and 9, plus essential nutrients like chlorophyll, phytosterols, and carotenoids.

Iwi Life responsibly sources its algae from sustainable farms in the USA, which require no fresh water. Plus, this heart health supplement is extensively tested for metals and contaminants, making it safe and high-quality. Give your heart the love it deserves with this premium plant-based supplement that’s ethical, effective, and environmentally friendly.

Product Pros
  • Effectively supports heart health
  • Plant-based and sustainable
  • Clinically proven for improved absorption
Product Cons
  • Doesn’t smell great in the bottle

Qunol Heart Health Supplement

Ideal for Stress Management
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The Qunol Ultra Coenzyme Q10 heart health supplement is specially formulated to be 100% water and fat-soluble, ensuring superior absorption compared to other CoQ10 products. In fact, clinical studies have shown that this supplement is absorbed three times better, making it one of the most effective on the market.

This supplement helps to restore energy levels that can be depleted with age and medication use. One of the best things is that it starts working quickly, with many users feeling improved energy levels within just a few weeks of taking it. And, with a four-month supply per package, this supplement is both convenient and affordable. It’s suitable for vegans and vegetarians, too, so anyone can enjoy its benefits. These heart health supplements are the perfect choice for anyone looking to improve their overall health and well-being.

Product Pros
  • Helps improve heart health
  • Protects against free radical damage
  • Improves muscle function, strength, and endurance
Product Cons
  • Relatively large capsules

Nature Made Heart Health Supplement

Improves Joint Health
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Nature Made fish oil is an excellent way to support your heart health. With 600 mg of Omega-3 fatty acids per capsule, including 500 milligrams of EPA and DHA, this supplement is ideal for anyone looking to maintain a healthy heart. What sets it apart from other fish oil supplements is its safety. This product undergoes a rigorous process to remove any contaminants or mercury, making it one of the safest fish oil supplements available. Plus, it’s gluten-free, dairy-free, and contains no artificial flavors or colors.

Not only is this heart health supplement safe, but it’s also effective. This means you can trust it to provide the optimal dose of Omega-3 fatty acids for heart health. Best of all, this is an easy-to-use supplement that fits seamlessly into your daily routine. Simply take two soft gels a day with water and a meal for the best results.

Product Pros
  • Excellent source of omega-3 fatty acids
  • Verified by United States Pharmacopeia (USP)
  • Helps keep cartilage healthy 
Product Cons
  • Some may notice a fishy aftertaste

Doctor’s Best Heart Health Supplement

Best for Cholesterol Management
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The Doctor’s Best High Absorption CoQ10 is designed to provide powerful support for heart health, energy production, and cell protection. Its natural fermentation process allows the body to easily absorb it. It’s also enriched with BioPerine, a black pepper extract that has been clinically shown to increase the absorption of CoQ10 in the body. This makes it an excellent choice for people who take statin drugs, as these drugs can deplete CoQ10 levels in the body.

Not only does this gluten-free supplement support heart health, but it also promotes vitality in multiple body systems, including the brain, immune system, skin, exercise capacity, and gum health. In short, this heart health supplement is a reliable and effective way to support heart health and energy production, making it a great addition to your daily health routine.

Product Pros
  • Improves sleep quality 
  • Helps with cholesterol levels 
  • Provides extra energy 
Product Cons
  • Effect varies from person to person

Buying Guide: Heart Health Supplements

Heart health supplements are an excellent addition to your daily routine to support your cardiovascular system and maintain your overall health. But, when it comes to choosing a heart health supplement, it’s important to be an informed consumer to make the right choice. To help you out, this comprehensive guide will walk you through the top factors to consider when selecting a supplement.

Ingredients

To choose the right heart health supplement, start by checking that it’s made with natural, high-quality ingredients that are scientifically proven to benefit your cardiovascular system. Look for supplements that contain Vitamins A and E, folate, Omega-3 fatty acids, garlic, CoQ10, and magnesium, as well as plant-based ingredients like hawthorn berry, ginkgo biloba, and green tea extract. Be cautious of supplements with artificial additives, which may have adverse effects on your health.

Quality

Choosing a trustworthy manufacturer is crucial when selecting a heart health supplement. Look for a manufacturer with a reputation for producing safe and effective products. Check for certifications or third-party testing results on their website to ensure the purity and potency of their supplements. Also, verify if the supplement is approved by the FDA or registered with the USP for quality assurance.

Dosage

Before taking any supplement, it’s important to determine if the recommended dosage is appropriate for your needs. Different ingredients may require different dosages depending on age, gender, health conditions, and so on, so it’s essential to consult with your doctor before taking any supplement. Additionally, make sure you understand any potential side effects and heed all warnings listed on the label or package insert.

Side Effects

It’s important to be mindful of potential side effects when taking a new supplement and consult with your doctor if any arise. Many heart health supplements contain active ingredients that may increase heart rate or blood pressure and could potentially cause other side effects like dizziness or headaches if used improperly. Always read the package insert and follow all instructions carefully before taking any supplement.

Formulation

When selecting a heart health supplement, make sure you get only what you need and avoid buying unnecessary fillers or ingredients that don’t have any real benefit. If you’re unsure of what specific formulation is right for you, consult with your doctor or a nutritionist who can provide tailored advice based on your personal needs and lifestyle.

Research

To make an informed decision when purchasing supplements, it’s crucial to conduct independent research. Read reviews from reputable sources such as medical journals as well as consumer feedback from other users who have used the product in question. This can help you get an understanding of how effective the product really is before investing in it.

Certification

Choose heart health supplements that are certified to be free of preservatives, artificial sweeteners, colors, or flavors. These ingredients could cause unwanted side effects if consumed over extended periods of time. Look for products certified by organizations like NSF International or USP, indicating that they meet high standards of purity and safety.

People Also Asked

Are heart health supplements safe to take?Are heart health supplements safe to take?

Heart health supplements can be safe to take when they are taken as directed and sourced from reputable brands. But, as with any supplement or medication, there may be potential side effects or interactions with other medications. It is recommended to speak with a healthcare provider before starting any new supplement regimen.

What ingredients should I look for in a heart health supplement?

When looking for a heart health supplement, you should consider ingredients such as Omega-3 fatty acids, Coenzyme Q10 (CoQ10), magnesium, and plant sterols or stanols. These ingredients have been shown to support cardiovascular health and can be found in many reputable heart health supplements on the market. That said, it is always recommended to consult with a healthcare professional before starting any new supplement regimen.

How much of a heart health supplement should I take daily?

The recommended daily dosage of a heart health supplement can vary depending on the specific product and its formulation. As such, it is important to follow the manufacturer's instructions and consult with a healthcare professional to determine the appropriate dosage for your individual needs. Generally, most heart health supplements recommend taking one or two capsules per day with a meal and a full glass of water.

Are there any side effects associated with taking heart health supplements?

There can be some side effects associated with taking heart health supplements, such as digestive distress or allergies. It is important to speak with a physician prior to taking any supplement to ensure that no interactions will occur with any medications or other supplements being taken.

Is there an age limit for taking heart health supplements?

There is no age limit for taking heart health supplements, as they can be beneficial for individuals of all ages. It is always recommended to consult with a healthcare professional before taking any supplements, however, particularly if you have any underlying medical conditions or are taking any medications. They can help determine if a heart health supplement is appropriate for you and what the appropriate dosage should be.

What are the benefits of taking a heart health supplement?

Taking a heart health supplement can provide a range of benefits such as supporting cardiovascular function, reducing the risk of heart disease, lowering blood pressure, and improving cholesterol levels. Additionally, some supplements can provide antioxidant support, boost energy levels, and enhance overall well-being.

Are there any drug interactions related to taking heart health supplements?

Yes, some heart health supplements can interact with certain medications. For example, Omega-3 supplements may increase the risk of bleeding when taken with blood thinners such as warfarin. CoQ10 supplements may interact with some cholesterol-lowering medications, such as statins. That’s why it's important to consult with a healthcare provider before taking any supplements, especially if you are currently taking medication.

Building a Stronger You

Supplement Institute is the fruit of extensive online publishing experience, spanning the breadth of SEO strategies to the nuances of paid advertisements. Our journey, marked by significant achievements and learning moments, inspires our core mission: to empower our readers with an abundance of information. By sharing insights and key learnings, we aim to provide you with the knowledge needed to navigate the complex world of supplements, helping you make well-informed decisions for your health and well-being. Welcome to Supplement Institute, where information is your greatest supplement.

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