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The Best Vitamins for Heart Health That Contain Essential Nutrients
Written By Supplement Institute Review Team
Supplements for heart health can help to fight heart disease, though they cannot cure the disease itself. Those who are at a higher risk of heart disease or suffering from a heart-related illness can benefit from these supplements as long as they don’t exceed the recommended dosage and don’t stop taking their essential medications.
We’ve reviewed the best vitamins for heart health in 2025 that contain vitamins and minerals scientifically proven to support the functioning of the heart. Our top pick, the Nutricost krill oil, delivers a robust dose of omega-3 fatty acids in an easily absorbed soft gel for optimal benefits.
The Best Vitamins for Heart Health of 2025
Nutricost Krill Oil
Best Overall
Unlock the potent benefits of fatty acids with Nutricost’s vitamins for heart healthm, with krill oil and omega-3 EPA and DHA. As a superior source of essential nutrients for your overall well-being, these soft gels contain a rich supply of EPA and DHA. These are the two key omega-3 fatty acids that have been recognized for their roles when it comes to supporting heart health, brain function, and overall vitality. Also, krill oil is derived from shrimp-like marine creatures, and it’s known for its remarkable bioavailability.
This means that these soft gels allow your body to efficiently absorb vital nutrients. This heart health vitamin offers a convenient and effective way to incorporate omega-3s into your daily routine. With their smaller design, they are easy to swallow, so you can enjoy the benefits of krill oil without the inconvenience of larger capsules. These soft gels are a valuable addition to any supplement routine, making them our top choice
KaraMD CoQ10 Plus
Supports Muscle Function
KaraMD’s CoQ10+ is a naturally sourced, vegan vitamin for heart health that provides holistic benefits to the cardiovascular system. This supplement contains two primary ingredients: magnesium glycinate and a coenzyme called “CoQ10”. The latter is a natural ingredient that is essential for supporting core functions that ensure a healthy heart and mind.
This potent formula is designed to support cardiovascular health in aging individuals. All the ingredients are naturally sourced from vegan sources and it’s designed to boost the overall energy levels with its gluten-free elements, which are readily absorbed by the stomach. This vitamin for heart health has a naturally sourced formula that holistically helps to improve heart health and provides various other benefits for an increased quality of life.
Qunol Ubiquinol CoQ10
Best CoQ10 Pick
Qunol’s extra strength ubiquinol soft gels contain an active form of CoQ10. As we age, our body’s ability to make and convert this enzyme from its inactive to its active form decreases significantly, making supplementation with this heart health vitamin vital.
The active CoQ10 in the form of ubiquinol is a powerful antioxidant that is beneficial in neutralizing free radicals and protects the cells from the damage caused by aging. It also supports healthy heart function by boosting the energy levels that are required for adequate blood circulation. This pick is a great solution to give your vascular system a boost.
Purely Holistic Red Yeast Rice
Easy to Ingest
Purely Holistic’s red yeast rice is an ideal heart health vitamin for those looking to support their cardiovascular system and maintain healthy cholesterol levels. This premium formulation is made with 1200mg of red yeast rice, as well as powerful ingredients like CoQ10 and niacin, providing a truly potent supplement designed to nourish the heart.
Not only does this vitamin for heart health offer a strong formulation, but it also contains 30% more capsules per bottle than competing products. As one of the largest supplement manufacturers in the USA, this brand is able to buy ingredients in bulk, allowing for larger bottles and lower prices. The red yeast rice extract itself is formulated to safely and naturally block the production of cholesterol in the liver, leading to better heart health over time. These vegetarian and dairy-free capsules are designed to be easy to swallow, have no taste, and require only one daily serving.
Nature’s Bounty Vitamin B12
Top B12 Pick
Nature’s Bounty vitamin for heart health is an exceptional supplement that offers multiple benefits for overall health. Supporting cardiovascular and circulatory systems, this option B-12 supplement supports the health of your nervous system. Beyond these benefits, it also aids in energy metabolism by helping the body convert food into cellular energy, ensuring that your body stays fueled throughout the day.
With a commitment to quality and safety, these quick-dissolve Vitamin B-12 tablets are gluten-free, sugar-free, and free from artificial flavors or sweeteners, making them suitable heart health vitamins for vegetarians. With over 50 years of dedication to quality, consistency, and scientific research, this brand continues to be a trusted wellness expert, delivering vitamins and nutritional supplements of unrivaled excellence.
Doctor’s Best CoQ10
Fast Absorbing
This high-absorption CoQ10 supplement by Doctor’s Best has bioprene, also known as black pepper extract, that enhances CoQ10 absorption in the body. When bioavailability of CoQ10 increases then the same amount of supplement provides more benefits.
Most aging people regularly take statin drugs to reduce high cholesterol levels in their blood. These drugs reduce the natural production of CoQ10 in the body. With this supplement, you can recuperate the depleted CoQ10 levels and also re-energize your body with its antioxidant properties.
Zhou Nutrition Vitamin D3 K2
Supports Bone Health
Zhou Nutrition’s Vitamin D3+K2 supplement is a great vitamin for heart health, but it also cheers you up with its D3 contents that are proven to improve mood. The Vitamin K2 in this supplement improves bone health and skin conditions, too.
K2 is scientifically proven to remove debris accumulated in the arteries. This debris consists of lipids, calcium, and dead cells. Within just 12 weeks, 50% of the calcium deposits are removed from arteries by taking Vitamin K2 regularly. This amazing combo of Vitamin D3 and K2 provides unique benefits for the heart, bones, mood, and brain.
Buying Guide: Vitamins for Heart Health
Millions of people suffering from heart diseases use dietary supplements to improve their heart function. Studies show that supplements can improve heart health and prevent congestive heart failure in people at high risk. Vitamin D, Vitamin K2, beta-carotene, and certain antioxidants all benefit heart health.
When arteries get clogged with the debris of cholesterol, fats, and dead cells, the risk of heart disease increases. In addition to regular exercise and an active lifestyle, you need supplements that clear this blockage, improve blood circulation, and strengthen the heart muscles. Vitamins for heart health are available in a wide range, but it’s hard to pick the right product or combination. Here’s a brief description of the most effective vitamins for the heart.
What Vitamins Are Effective for Heart Health?
CoQ10
CoQ10, also called ubiquinone, is a coenzyme that is naturally produced in the body. Many food groups such as organ meats, green vegetables, and citrus fruits also contain CoQ10. The function of CoQ10 is to act as a strong antioxidant that protects the cells. It also plays a crucial role in the metabolism process. Dr. Jannine Kraus, doctor, acupuncturist, and podcaster, says, “CoQ10 is an enzyme that helps muscles, including the heart muscle make more energy. It does this by helping the energy-making chemical reactions in the factories in every muscle aka mitochondria, do their job more efficiently.”
Most people may not need a supplement of CoQ10 as it is naturally found in the body. However, research shows that deficiency of this supplement can occur with increasing age. Adding a supplement in the form of CoQ10 can be beneficial for some and there are many different conditions that you can treat with CoQ10. Studies show that CoQ10 supplements help lower blood pressure.
It’s also recommended for treating different heart conditions, including lowering the risk of heart failure. This vitamin can improve certain heart-related symptoms and is also beneficial in reducing the risks associated with cardiac arrest. Keep in mind that your recommended heart medication must be continued along with the supplement. When taking other heart medicines, the CoQ10 supplement should only be added to your daily supplement routine after consulting with your doctor.
Evidence also shows that CoQ10 supplements are helpful in lowering adverse effects related to muscle pains, aches, and liver problems, which occur when a person is taking statin drugs to treat cholesterol. It can also slow down the progression of Alzheimer’s disease and can be helpful if you’re suffering from any type of cardiovascular disease.
Vascular problems are related to the network of nerves that support our circulatory system. Vascular diseases can disrupt the function of our arteries, veins, and vessels, affecting blood flow in our body. As a result, our tissues do not get enough blood, which might result in a condition called ischemia. When any issue occurs in coronary arteries that supply blood to the heart, a person can feel angina (chest pain) or experience a heart attack. Arteries that supply blood to other tissues are peripheral. Both coronary and peripheral arteries can get blocked due to the deposition of cholesterol or fat, resulting in a low blood supply to the heart and other tissues and organs.
Several other benefits of taking a supplement of CoQ10 relate to lowering the frequency of migraines, headaches, and muscular dystrophy. It is also linked with boosting energy levels and improving the overall blood flow in the body.
Vitamin B12
Research shows that Vitamin B12 can improve heart health by reducing homocysteine levels in the blood. According to research, the deficiency of Vitamin B12 can lead to elevated levels of homocysteine in the blood. Homocysteine is an amino acid that is linked with increasing the risk of heart disease.
Krause states, “B12 has a role in the breakdown of homocysteine,” so supplementation reduces the levels of homocysteine in the blood and lowers the risk of heart problems. Besides homocysteine breakdown, Krause highlights other areas where B12 affects heart health, including “in choline production, a key amino acid necessary for healthy nerve signaling to the heart.”
Vitamin K2
Vitamin K2 is strongly linked with the prevention of heart disease. Doctors tend to prescribe K2 supplements if a patient over 40 has a family history of heart disease. The buildup of calcium and lipids in the arteries can cause blockages, leading to hypertension and heart disease. K2 is beneficial in preventing this build-up in the arteries and clears it away with time.
Studies show that people taking Vitamin K2 regularly have a reduced risk of calcification in arteries by 52% and a lowered risk of heart disease by 57%. In another study, conducted on female participants consuming 10 micrograms of Vitamin K2 daily, revealed that the risk of heart disease was reduced by 9%.
Vitamin D
It’s believed that increasing the intake of Vitamin D is beneficial for those who are at risk of congestive heart failure. Studies show that people who have suffered from chronic heart failure and who took Vitamin D supplements for 12 months resulted in improved cardiac function as compared to those who were on a placebo.
Vitamin D is a safe and inexpensive option to reduce the risk of chronic heart failure. Vitamin D is made naturally in our body by direct exposure to sunlight. It is also found in certain foods, including cheese, eggs, liver, and fatty fish. Fortified food groups also contain Vitamin D, such as cereals, milk, and soy. Your doctor may recommend a Vitamin D supplement if you have suffered from congestive heart failure. As with all vitamins, be careful not to exceed the recommended dosage as prescribed by your doctor.
Red Yeast
Red yeast is especially beneficial to those dealing with high cholesterol, as it can lower blood cholesterol as well as your overall cholesterol levels with regular intake. It can also enhance your overall heart health and kidney function, targeting and improving your body’s most important organs.
It also may reduce inflammation, cancer cell growth, and risk factors of metabolic syndrome in some people. Check to ensure the red yeast rice product you’re purchasing contains the key ingredient statin, which can significantly lower levels of cholesterol and contribute to better well-being in the long term. This will guarantee you see some benefits from this super helpful supplement when added to your daily routine.
People Also Asked
Which vitamins should I take to maintain a healthy heart?
Doctors recommend increasing your fiber intake and supplementing your diet with omega 3, Vitamin D, and magnesium if you want to reduce the risk of heart disease. People with heart problems can strengthen their hearts by supplementing their diet with CoQ10 or Vitamin K2. Regular exercise and stress-reducing herbal teas are also beneficial for maintaining a healthy heart.
Do vitamins for heart health control palpitations?
Heart palpitations often result because of inflammation in the body or oxidant stress. Studies show that Vitamin C, magnesium, and Vitamin D intake can reduce heart palpitations.
Which foods should I avoid if I’m suffering from a heart disease?
Those who are already suffering from a heart disease should lower their choline intake. Choline is present in meat, eggs, and milk. Excess choline increases the bacteria-producing compound TMAO (trimethylamine N-oxide) in the body and also causes the clumping of platelets to form clots.
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