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Best Brain Support Supplements to Sharpen Your Mind in 2025
Written By Sarah Radford
Many individuals can benefit from the use of brain support supplements. These compounds work together to support cognitive function with the ability to improve memory, concentration, motivation, creativity, and more. These supplements typically include ingredients like Omega-3 fatty acids – which increase learning, memory, or cognitive function – or L-theanine – which contributes to enhanced memory and executive function.
We’ve compiled a list of the best brain support supplements to help enhance your mental performance in 2025. Read below for some notable options, starting with our top choice—the Royal Jelly Brain Fuel supplement by Beekeeper’s Naturals. Its natural ingredients like Ginkgo biloba and Bacopa monnieri can improve clarity and focus while providing a caffeine-free energy boost.
The Best Brain Support Supplements
Beekeeper’s Naturals Royal Jelly Brain Fuel
Best Overall
Beekeeper’s Naturals Royal Jelly Brain Fuel is designed to naturally enhance memory, focus, and productivity. Their powerful blend of adaptogens combines 500mg of royal jelly with ginkgo biloba and bacopa monnieri to provide antioxidants and nutrients that promote mental clarity, improve cognition, and enhance focus and memory. This Brain Fuel supplement helps you get through the mid-day slump, early morning wake-up, or late night with a natural energy boost without any caffeine.
This antioxidant-rich formula derived from nature supports overall brain health by combating brain fog and jet lag. It’s third-party and lab-tested to guarantee purity and is free from artificial preservatives, colors, and common allergens, making it a clean and effective choice. It’s the best overall product for those seeking a natural cognitive enhancement.
Zhou Energy + Focus Brain Support Supplement
Most Energizing
Zhou Nutrition’s brain support supplement, Energy + Focus, offers a unique blend of caffeine and L-theanine to deliver sustained energy and mental clarity without unwanted side effects. Their unique 2:1 ratio of L-Theanine to caffeine provides smooth and focused energy so you can take on the day without jitters or crashes. Zhou provides a great option for those craving an energy boost without the sugar and calories common in most energy drinks.
This brain support supplement promotes a sense of calm, enhancing mental focus and confidence. Energy + Focus offers a healthy option formulated from all-natural sources without unwanted chemicals. Zhou ensures the highest quality by using Good Manufacturing Practices (GMP) with premium ingredients in its Utah-based lab, giving you confidence in the product’s safety and effectiveness.
Qualia Mind Brain Support Supplement
Vegan, Gluten-Free, Non-GMO Option
The Qualia Mind Brain Support Supplement is a remarkable brain booster renowned for its ability to enhance memory, focus, and concentration. With a potent blend of ingredients like Ginkgo biloba, Alpha GPC, Bacopa monnieri, and DHA, all encapsulated in a convenient 154-count bottle, it’s great for helping to increase your productivity during those long work days.
This supplement isn’t just about enhancing cognitive functions. It’s also your go-to mood enhancer, fostering a balanced mood and reducing stress. Quickly absorbed, this potent supplement fuels your brain, empowering you to stay focused and clear-headed all day long. In short, it’s not just about improving cognition; it’s about transforming it. When I need to focus on a complex task at work, I know this supplement can support me cognitively while enhancing my mood. So if you’re on the hunt for a vegan, gluten-free, and non-GMO supplement that actively boosts focus, clarity, and mood, check out this one!
Iwi Brain Support Supplement
Most Potent
The Iwi brain support supplement offers a cutting-edge nootropic Omega-3 formula to enhance memory and focus with superior absorption rates. Iwi combines premium plant-based ingredients such as algae-derived DHA to support memory, EPA to support nervous system function, phosphatidylserine to support mental acuity, and green coffee bean extract for antioxidants. These nootropic ingredients combine to support sharpness and focus while nourishing mood and overall mental performance.
Unlike traditional fish oil supplements, Iwi’s Omega 3 fatty acid capsules are tasteless, easy to swallow, and gentle on the stomach. The brand prioritizes environmental sustainability by using algae grown in the desert with sun and saltwater to provide a vegan and ocean-friendly product. Its innovative blend of nourishing fats and essential vitamins offers brighter cognitive energy at an affordable price, making it an excellent choice for those seeking brain support without breaking the bank.
Nutricost Vitamin B6 (Pyridoxine HCI)
Best Value
Nutricost’s Vitamin B6 Capsules offer a convenient and cost-effective solution for obtaining Vitamin B6 with each of the 240 capsules containing 100mg of high-quality Pyridoxine HCl. Research shows vitamin B6 can impact cognitive performance by improving recall, attention, and working memory. Since your body can’t produce vitamin B6 it’s important to obtain it through food or supplements. Supplementation can also support serotonin production to reduce anxiety and mood disorders.
This supplement is manufactured in a facility compliant with Good Manufacturing Practices (GMP) and is registered with the FDA, ensuring stringent quality control measures. Every batch undergoes thorough testing by independent, ISO-accredited laboratories, guaranteeing purity and potency. With this brain support supplement, you can trust you’re receiving a reliable and high-quality product at an affordable price.
VitaRaw Lion’s Mane Cognitive Enhancement
Best Absorption
VitaRaw’s Lions Mane Capsules feature organic lion’s mane mushrooms that contain a full spectrum of vitamins and minerals. These capsules deliver the optimal compounds essential to optimize the Nerve Growth Factor (NGF) to support neural health. VitaRaw’s capsules are rich in beta-glucan – a form of fiber found in mushrooms that has been linked to improved memory. They use a hot water extraction method to preserve the beta-glucans often evaporated through the harsh dual extraction method other brands commonly use.
These capsules contain real mushroom fruiting bodies while many competitor brands use mycelium roots – roots grown on grains that add unnecessary grains to the brand’s powder capsules. VitaRaw adds black pepper to their formula to increase the bioavailability of 2390mg of organic lion’s mane powder extract to provide the optimal dose for brain support, improved memory, and focus. Each batch is carefully tested for purity and safety to ensure you’re receiving only the highest quality product.
Neuriva Brain Performance Supplement
Most Convenient
Neuriva designed its Brain Health Plus supplement to enhance memory, focus, and overall brain performance so you can unlock your full potential. Its clinically tested formula combines coffee cherry Neurofactor, plant-sourced phosphatidylserine, and essential B vitamins, such as B6 and B12, to promote optimal brain health. This formula stands out with clinically tested neurofactor, derived from whole coffee fruit extract, that increases vital neuroprotein BDNF levels. This facilitates crucial connections between brain cells and supports synaptic plasticity and neuronal survival.
B vitamins are added to enhance brain energy production, neurotransmitter synthesis, and mood support. Neuriva prioritizes quality using vegetarian, gluten-free, non-GMO, and decaffeinated ingredients to ensure premium quality and peace of mind. These supplements are backed by a commitment to freshness, purity, and labeled potency. They even built the Neuriva Brain Gym app, available on the App Store or Google Play, for customers to track long-term cognitive performance to optimize their supplements.
Onnit Alpha Brain Support Supplement
Best Ingredients
Onnit’s Alpha Brain support supplement offers a caffeine-free blend to support memory, promote focus and mental processing, and help improve flow state (also known as being “in the zone”). Taking two capsules daily can help you stay more focused on tasks, think more clearly, and react more quickly.
By incorporating scientifically studied ingredients, Onnit’s Alpha Brain support supplement helps optimize cognitive abilities. They use a unique blend of Vitamin B6, herbal extracts, and amino acids to support memory and focus. It contains no caffeine or gluten, making it a safe choice for those with sensitivities.
Vital Vitamins Brain Booster
Most Reliable
The Vital Vitamins Brain Booster is formulated to elevate cognitive performance and enhance brain power. Designed with ingredients such as Ginkgo biloba, Vitamin B12, and DMAE, this nootropic blend aims to improve focus, memory, clarity, and energy without the jitters or crashes often associated with caffeine-based supplements.
Taking 1 capsule per day can heighten energy levels, reduce fatigue, and enhance cognitive function, making this supplement a great choice for those seeking peak mental performance in their daily lives. Vital Vitamins included a mix of vitamin B12, ginkgo biloba, and DMAE to help promote improved cognitive energy and a sustained energy boost without caffeine. They prioritize responsibly sourced, high-quality ingredients to ensure you only get what you need.
Nature’s Craft Neuro Health Supplement
Best Focus
Nature’s Craft designed their Neuro Health nootropic complex to enhance memory, focus, and cognitive clarity. They packed each serving with a unique blend of vitamins and minerals such as Inositol, Bilberry, Huperzine A, DHA, Magnesium, and more to optimize brain health and performance. Taking 2 capsules daily can increase mental clarity, energy, concentration, and alertness.
Their formula was built with essential nutrients like Vitamin E, Vitamin A, Vitamin B6, Niacin, and GABA to support attention and cognitive function. Ingredients such as Bacopa monnieri, Licorice root, Magnesium, and Chromium picolinate work together to combat brain fog and promote cognitive clarity. Nature’s Craft relied on years of scientific research and sourced only the best ingredients to ensure you receive the best product possible. Each batch is manufactured in American GMP facilities and undergoes rigorous third-party testing for purity and potency.
Brain Support Supplements: A Buying Guide
In the fast-paced world we live in it’s so important to keep your mind healthy and active. Brain support supplements can help keep your brain in peak shape so you can stay sharp as you age and change throughout your life. Brain support supplements can help improve the ability to concentrate, learn, and work by improving memory, focus, and cognitive ability.The brain support supplement market is saturated making finding the right supplement brand overwhelming. We put together this comprehensive guide to educate you in the world of nootropics and help you make an informed buying decision.
What to Consider When Buying a Brain Support Supplement
Read below to learn about a few important factors to consider when purchasing a brain support supplement:
Ingredients
Always evaluate the ingredients that go into a supplement. Look for a brand that uses only natural ingredients and avoids artificial ingredients or fillers. The more natural ingredients that are used, the safer the product.You should only buy ones made with your health and safety in mind. Ingredients such as choline, Zinc, B vitamins, and Omega-3 fatty acids are commonly integrated into brain support supplements to enhance cognitive abilities. Always air on the side of caution and research the ingredients listed in any supplement you consider purchasing.
Brand name
A brand’s reputation in creating and distributing other supplements can indicate whether that company participates in safe production practices. Reputable brands are more likely to create a product with safe ingredients that you can trust.If you’re unfamiliar with a brand, research the company’s background to learn more about its reputation with customers and manufacturing practices. Avoid purchasing supplements from companies that don’t provide information online as you don’t want to risk taking tainted or unsafe supplements.
Reputation
Search for companies with a positive reputation and history in manufacturing brain health supplements. Companies manufacturing brain supplements for at least the past five years or more should have a strong track record for producing reputable products. Find a company’s history under the “About” section on its website. Scroll through product reviews to learn more about customer experiences with the brand so you can build an informed opinion before making a decision.
Cautions
Brands list potential side effects and drug interactions on the back of the supplement bottle. Read through these to ensure you’re familiar with potential side effects and confirm that the product is suitable for you. Some products caution consumers who are pregnant or over/ under a certain age against use; read over the entire bottle so you understand all the potential risks associated with it.
Side effects
Pay close attention to any side effects you may experience when taking a new supplement. If you experience dizziness, headaches, heart palpitations, constipation, or allergic skin reactions, stop using the supplement immediately and consult your doctor.
Allergies
Always inspect the supplement bottle closely to ensure nothing on the ingredient label will negatively affect you. If you have a pre-existing allergy, thoroughly examining the ingredient list becomes even more important. Ensure the product you choose doesn’t contain anything you may be sensitive or allergic to.
Customer feedback
Consumers with experience using brain health supplements often offer helpful advice and feedback regarding their experiences. Read through customer reviews on Amazon to learn whether other consumers had positive or negative experiences with a supplement. You can learn from those who have already purchased and used a supplement you’re considering.
Price
It’s important that your purchase provides a high value and fits your budget. Higher price tags don’t always translate to excellent quality, so try to find a balance between your budget and the features offered.
Certifications
A Quality Assurance certificate is a recognized assurance of the quality of a product. Some reputable certifications to look out for include an endorsement by the FDA (Food and Drug Administration) or a Certificate of Analysis.
Health care professional
Before adding any new supplement to your routine, consult your doctor. They will provide the best advice about using a new product and whether it is compatible with your body. If you have allergies, health challenges, or questions about an ingredient or product, consult your healthcare professional to ensure new supplements are conducive to you.
Personal preference
Since we’re all human and our bodies are built differently, not every product will work the same for each individual. Sometimes it’s not the product itself, but how your body uniquely reacts to that product. That is why a brain supplement can improve one user’s brain health but have no impact on someone else. Taking a new supplement can certainly have a trial-and-error period to see if it’s suitable for you.
What Foods Can Act as Natural Brain Health Supplements?
Brain supplements should be just that – a supplement to your current diet or routine. Take brain support supplements with natural food sources to optimize your results. Below, we discuss foods that can help increase brain power and promote brain function.These foods contain natural vitamins and minerals that can help prevent cognitive decline and even keep diseases like Parkinson’s and Alzheimer’s disease away.
Fatty fish – Omega-3 fatty acids
Omega-3s are healthy unsaturated fats found commonly in fatty fish, such as sardines and salmon. Research has linked omega-3’s with lower levels of beta-amyloid – a protein found in folks with Alzheimer’s disease. EPA and DHA are two omega-3 fats that come primarily from cold-water fish. These fats are the most abundant fatty acids in the brain that help reduce inflammation in the body and are linked to improved cognitive function.
Eggs
Egg yolks contain a chemical compound known as choline. Acetylcholine is a neurotransmitter released when you eat egg yolks that helps you stay sharp, boosts memory, and improves concentration.
Spinach and Leafy Green Vegetables
Spinach and leafy greens are rich in vitamin K, lutein, folate, and beta-carotene – all nutrients that support brain health. Eating your greens has been scientifically linked to decreasing cognitive decline, meaning Popeye was on to something with all the spinach he ate.
Dark chocolate
Cocoa beans are the primary ingredient in chocolate and contain flavanol, a form of flavonoids with anti-inflammatory and antioxidant effects. Studies have linked chocolate consumption to increases in memory and reaction time in both the short term and long term.
Green tea
Green tea has been consumed for thousands of years and has become increasingly popular in Western culture. Researchers linked regular green tea consumption with decreases in anxiety and increases in cognition and brain function.
Coffee
Coffee is beloved by many and has cognitive benefits beyond the joy of sipping on your morning cuppa. Coffee can improve mood, alertness, learning, and reaction time and has been linked to diminished risk of Alzheimer’s and Parkinson’s diseases.
People Also Asked
What are brain support supplements?
Brain support supplements are made up of vitamins and minerals with the intention to improve memory, cognitive abilities, and focus.
Do I need to take a brain support supplement?
A brain support supplement is by no means necessary but can certainly help you stay sharp. A healthy diet can supply many of the vitamins and minerals we need for a healthy brain, but sometimes we miss out on some due to dietary preferences. Supplementation can help fill any of these holes we have in our diet.
What types of ingredients are found in brain support supplements?
Some common ingredients include Omega-3 fatty acids, L-theanine, Panax ginseng, Bacopa monnieri, Ginkgo biloba, Rhodiola rosea, Phosphatidylserine, Lion's mane mushroom, Creatine, and caffeine. These ingredients are known cognitive enhancers and brands combine them in unique ratios to maximize brain function.
How can I stimulate my brain naturally?
Brain exercises can help improve brain health alone or in combination with brain support supplements. Reading, meditation, word puzzles, or math problems help the brain avoid age-related degeneration.
How can I know if a brain support supplement is legit?
Always check that the brain support supplements you’re considering have approval from the FDA. The FDA, or Food and Drug Administration, approves dietary supplements when they’ve deemed that the benefits outweigh the risks. The FDA aims to protect public health and their approval is a reputable way to check the safety of a supplement.
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